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What is the most potent estrogen? Estradiol (sometimes known as E2) is the most potent estrogen. In women it's produced by the ovaries. Estriol (sometimes known as E3) is produced during pregnancy.
Can estriol cause weight gain? Lower levels of estradiol may lead to weight gain. Throughout their life, women may notice weight gain around their hips and thighs. However, after menopause, women tend to gain weight around their mid-section and abdomen.
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